| Rank | Bib | Name | Affiliation | Time | Split Time | Laps | Category |
| 1 | 1 | Maghalie ROCHETTE | Specialized X Feedback Sports | 40:46. | 10:22. | 4 | WE |
| 2 | 4 | Caroline MANI | Pactimo/ Colorado Proud | 42:15. | 10:54. | 4 | WE |
| 3 | 6 | Ruby WEST | Pivot Maxxis P/B Stans NoTubes | 42:23. | 10:46. | 4 | WE |
| 4 | 10 | Sunny GILBERT | Pactimo/ Colorado Proud | 42:29. | 10:33. | 4 | WE |
| 5 | 8 | katie CLOUSE | Cannondale p/b Cyclocross world | 42:43. | 10:49. | 4 | WE |
| 6 | 5 | Courtenay MCFADDEN | Pivot Maxxis pb Stans NoTubes | 42:54. | 10:57. | 4 | WE |
| 7 | 3 | rebecca FAHRINGER | Kona Maxxis Shimano | 43:11. | 10:47. | 4 | WE |
| 8 | 2 | Clara HONSINGER | Team S&M CX | 43:18. | 10:43. | 4 | WE |
| 9 | 13 | Madigan MUNRO | Boulder Junior Cycling | 43:30. | 10:40. | 4 | WE |
| 10 | 9 | Jennifer JACKSON | Easton-Giant p/b Transitions Li | 43:40. | 11:02. | 4 | WE |
| 11 | 11 | Raylyn NUSS | MAAP | MINI U.S. Cyclocross Pro | 44:33. | 11:12. | 4 | WE |
| 12 | 7 | Samantha RUNNELS | Squid x Eliel | 44:53. | 11:22. | 4 | WE |
| 13 | 16 | Hannah ARENSMAN | J.A. King cyclocross | 44:59. | 11:03. | 4 | WE |
| 14 | 15 | Erica ZAVETA | The Pony Shop p/b KPMG | 45:21. | 11:01. | 4 | WE |
| 15 | 12 | Crystal ANTHONY | Liv Racing | 45:45. | 11:34. | 4 | WE |
| 16 | 27 | Amanda NAUMAN | SDG - Muscle Monster | 45:59. | 11:48. | 4 | WE |
| 17 | 17 | Jennifer MALIK | Red Kite Fund pb BikeFettish | 46:14. | 11:36. | 4 | WE |
| 18 | 32 | Emily PAYONK | Team NeighborLink | 46:32. | 11:26. | 4 | WE |
| 19 | 26 | Lizzy GUNSALUS | Cannondale p/b cyclocrossworld. | 46:47. | 11:53. | 4 | WE |
| 20 | 20 | Emily WERNER | Amy D. Foundation | 47:02. | 11:59. | 4 | WE |
| 21 | 22 | Lauren ZOERNER | Alpha Bicycle Company Groove Su | 47:11. | 11:41. | 4 | WE |
| 22 | 21 | Bridget TOOLEY | Easton-Giant p/b Transitions Li | 47:21. | 12:02. | 4 | WE |
| 23 | 14 | Maria LARKIN | Donkey Label Racing p/b FK Law | 47:29. | 11:46. | 4 | WE |
| 24 | 19 | Shannon MALLORY | NWCX Project | 47:35. | 12:02. | 4 | WE |
| 25 | 18 | Turner RAMSAY | Alpha-Bicycle Co.-Groove Subaru | 48:37. | 12:27. | 4 | WE |
| 26 | 24 | Cassidy HICKEY | Bear Development | 49:28. | 12:33. | 4 | WE |
| 27 | 41 | Daniela MEHECH | Bike Ohio | 49:35. | 12:06. | 4 | WE |
| 28 | 23 | Ellie MITCHELL | NWCX Project | 49:56. | 12:24. | 4 | WE |
| 29 | 45 | Caitlin NEUMAN | | 50:06. | 12:25. | 4 | WE |
| 30 | 30 | Siobhan KELLY | Black Dog Racing | 50:12. | 12:33. | 4 | WE |
| 31 | 46 | Eleanor DYAS | Blue Ridge Cross p/b JA King | 50:28. | 12:44. | 4 | WE |
| 32 | 28 | Aubrey DRUMMOND | SPCX p/b RK Black | 50:37. | 12:56. | 4 | WE |
| 33 | 40 | Ryley MOSHER | Wheel Works Racing | 50:50. | 12:47. | 4 | WE |
| 34 | 42 | Tea WRIGHT | Boulder Junior Cycling | 51:06. | 12:59. | 4 | WE |
| 35 | 25 | Katja FREEBURN | Linear Sport | 51:15. | 12:44. | 4 | WE |
| 36 | 47 | Laura RICE | Blue Ridge Cross | 52:46. | 14:05. | 4 | WE |
| DNS | 44 | Allison ARENSMAN | JA King Cyclocross | | 16. | 1 | WE |
| @1Lap | 31 | Kaia SCHMID | New England Devo p/b Cadence We | | 13:11. | 2 | WE |
| @1Lap | 48 | Traci JUDGE | | | 12:58. | 2 | WE |
| @1Lap | 29 | Abigail YATES | Matrix/RBM | | 13:54. | 2 | WE |
| @1Lap | 43 | Danielle CLARK | Blue Ridge Cross | | 13:19. | 2 | WE |
| DNF | 49 | Molly LOHRY | | | 12:52. | 2 | WE |
