| Rank | Bib | Name | Affiliation | Time | Split Time | Laps | Category |
| 1 | 405 | Megan BARR | Save the BWCA Cycling Team p/b | 42:57. | 8:39. | 5 | W 1-2 |
| 2 | 407 | Corey COOGAN CISEK | Amy D. Foundation | 43:13. | 8:42. | 5 | W 1-2 |
| 3 | 445 | Kelly LAWSON | Hardwood Next Wave Cycling Team | 44:07. | 8:38. | 5 | W 1-2 |
| 4 | 424 | Julie SAELER | Trek Cyclocross Collective | 44:25. | 8:53. | 5 | W 1-2 |
| 5 | 403 | Elizabeth SHELDON | Crosshairs Cycling | 44:45. | 9:00. | 5 | W 1-2 |
| 6 | 402 | Alexandra CAMPBELLFORTE | Vanderkitten CX | 45:18. | 9:05. | 5 | W 1-2 |
| 7 | 443 | Mary PENTA | | 46:01. | 8:47. | 5 | W 1-2 |
| 8 | 412 | April BEARD | Trek Midwest Team | 46:11. | 9:17. | 5 | W 1-2 |
| 9 | 439 | Jennifer BINKOWSKI | Trek Midwest Team | 46:55. | 9:25. | 5 | W 1-2 |
| 10 | 434 | Risa HUSTAD | Taco Cat Racing | 47:05. | 9:26. | 5 | W 1-2 |
| 11 | 447 | Kenda SUPER | Hagens Berman Cycling | 47:08. | 9:19. | 5 | W 1-2 |
| 12 | 422 | Aubrey DRUMMOND | SPCX p/b R.K. BLACK | 47:11. | 9:48. | 5 | W 1-2 |
| 13 | 451 | Heidi BECK | Velocause Centraal Cycling | 47:16. | 9:26. | 5 | W 1-2 |
| 14 | 428 | Carly THOMSEN | Orion Racing p/b Borah Teamwear | 47:30. | 9:20. | 5 | W 1-2 |
| 15 | 438 | Terra KIER | Rebel West CX | 47:35. | 9:34. | 5 | W 1-2 |
| 16 | 429 | Anne MAYER | Trek Midwest Team | 47:56. | 9:52. | 5 | W 1-2 |
| 17 | 452 | Katelyn WALCROFT | | 48:02. | 9:36. | 5 | W 1-2 |
| 18 | 430 | Eleanor DYAS | Midwest Devo | 48:10. | 9:54. | 5 | W 1-2 |
| 19 | 420 | Melissa SEYMOUR | Team O2 | 48:33. | 9:38. | 5 | W 1-2 |
| 20 | 436 | Andrea CYR | Velocause Centraal Cycling | 48:42. | 9:37. | 5 | W 1-2 |
| 21 | 414 | Leslie ETHRIDGE | ORNOT | 48:53. | 9:41. | 5 | W 1-2 |
| 22 | 418 | Alex CARLSON | Cycle-Smart | 48:53. | 9:42. | 5 | W 1-2 |
| 23 | 427 | Amanda MACK | Trek Midwest Team | 48:59. | 9:39. | 5 | W 1-2 |
| 24 | 442 | Vanessa CURTIS | University of Iowa Heart and Va | 49:12. | 9:42. | 5 | W 1-2 |
| 25 | 425 | Lily PECK | Womens CX Project | 49:16. | 9:42. | 5 | W 1-2 |
| 26 | 416 | Emily PAYONK | Team NeighborLink | 39:43. | 9:00. | 4 | W 1-2 |
| 27 | 415 | Julie PHELPS | Gryphon Velo Racing | 39:58. | 10:08. | 4 | W 1-2 |
| 28 | 431 | Lindsay KNIGHT | Tenspeed Hero | 40:15. | 10:01. | 4 | W 1-2 |
| 29 | 419 | Michelle HANCE | Team Handmade | 40:25. | 10:27. | 4 | W 1-2 |
| 30 | 435 | Ashley HEIDENREICH | Half Acre Cycling | 40:39. | 9:56. | 4 | W 1-2 |
| 31 | 437 | Lori NEDESCU | 3T/Q+M | 41:31. | 10:23. | 4 | W 1-2 |
| 32 | 417 | Jennifer YOUNGWERTH | Team Wheel & Sprocket | 41:34. | 10:26. | 4 | W 1-2 |
| 33 | 450 | Jessica WHITON | xXx Racing | 43:04. | 10:35. | 4 | W 1-2 |
| 34 | 440 | Sarah BARBER | CRANDIC Racing Club | 44:15. | 10:45. | 4 | W 1-2 |
| DNF | 400 | Regina LEGGE | Trek Cyclocross Collective | | 8:29. | 1 | W 1-2 |
